Assessment of Blood and Renal Function Profiles in Pregnant Women from Narowal, Pakistan

Abstract

Pregnancy is a period during which one or more embryo develops into offspring inside the human's female womb in nine months. During three trimesters of pregnancy many physiological changes such as mood swings, back pain, hair loss, excess melanin production, and fluctuation in hematology and serology happen. Blood samples of pregnant ladies and control were taken and subjected to hematological and renal functioning tests in order to check either these parameters can be the biomarkers of pregnancy or not. Sampling was done in certain hospitals and laboratories in Narowal, Punjab, Pakistan from February 2021 to June 2022. Blood samples of 160 pregnant women and160 control women were collected in EDTA coated vials and subjected to investigation of Complete Blood Count. On the other hand, blood samples of 51 pregnant women and 51 control were collected in serum Vials, serum was extracted and renal functioning were analyzed. A statistically significant difference was found by t-test on hematological parameters including hemoglobin (Hb), hematocrit (HCT) and white blood cells (WBC). Investigation of renal functioning of pregnant ladies in comparison to control revealed a distinctive difference with the highest variation in the blood urea (p=0.0002) and serum creatinine (p=0.0003) contents. This study indicates that certain hematological as well as renal functioning tests can serve as biomarkers of pregnancy. Further study will evaluate these parameters for a bigger sample size to give a more accurate and precise information.