Assessment of Blood and Renal Function Profiles in Pregnant Women from Narowal, Pakistan

Authors

  • Fizza Azeem Applied Molecular Biology and Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan.
  • Rabia Mehmood Institute of Zoology University of Punjab, Lahore, Pakistan
  • Rahat Raza Rasheed Department of Zoology, University of Okara, Okara, Pakistan
  • Amna Rehman Institute of Zoology, University of the Punjab, Lahore, Pakistan.
  • Muhammad Zohaib Department of Zoology, Government College University, Lahore, Pakistan.
  • Suneela Amaan University of Veterinary and Animal Sciences (UVAS), Lahore, Pakistan
  • Zoya Asif Applied Molecular Biology and Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan.
  • Tayyba Jan Department of Zoology, Lahore College for Women University (LCWU), Lahore, Pakistan.
  • Hanan Afzal Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.
  • Sadia Ahmad Institute of Zoology, University of the Punjab, Lahore, Pakistan.
  • Kaleem Maqsood Department of Biology, Lahore Garrison University, Lahore
  • Ali Afzal University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Muddasir Hassan Abbasi Department of Zoology, University of Okara, Okara, Pakistan
  • Nadeem Sheikh Institute of Zoology, University of the Punjab, Lahore, Pakistan.
  • Muhammad Babar Khawar Applied Molecular Biology and Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan.

DOI:

https://doi.org/10.24312/ucp-jst.02.02.428

Keywords:

Pregnancy, Complete Blood Count, Hematology, Renal Functioning Test, Biomarker

Abstract

Pregnancy is a period during which one or more embryo develops into offspring inside the human's female womb in nine months. During three trimesters of pregnancy many physiological changes such as mood swings, back pain, hair loss, excess melanin production, and fluctuation in hematology and serology happen. Blood samples of pregnant ladies and control were taken and subjected to hematological and renal functioning tests in order to check either these parameters can be the biomarkers of pregnancy or not. Sampling was done in certain hospitals and laboratories in Narowal, Punjab, Pakistan from February 2021 to June 2022. Blood samples of 160 pregnant women and160 control women were collected in EDTA coated vials and subjected to investigation of Complete Blood Count. On the other hand, blood samples of 51 pregnant women and 51 control were collected in serum Vials, serum was extracted and renal functioning were analyzed. A statistically significant difference was found by t-test on hematological parameters including hemoglobin (Hb), hematocrit (HCT) and white blood cells (WBC). Investigation of renal functioning of pregnant ladies in comparison to control revealed a distinctive difference with the highest variation in the blood urea (p=0.0002) and serum creatinine (p=0.0003) contents. This study indicates that certain hematological as well as renal functioning tests can serve as biomarkers of pregnancy. Further study will evaluate these parameters for a bigger sample size to give a more accurate and precise information.

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Published

2025-07-28

How to Cite

Assessment of Blood and Renal Function Profiles in Pregnant Women from Narowal, Pakistan. (2025). UCP Journal of Science & Technology, 2(2), 01-07. https://doi.org/10.24312/ucp-jst.02.02.428